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It is well known that oral delivery of proteins and peptides generally involves the coadministration of enzyme inhibitors and/or penetration enhancers, to inhibit proteolytic enzymes and promote the macromolecule permeation, respectively (Sinha et al., 2007)

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doi: 10.3390/jcm7100342 37 CompstonA.ColesA

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Effects on cellular NAD+ and SAM pools in vitro