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Keywords: ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking 1 Introduction Ulcerative colitis (UC) is a chronic, relapsing form of inflammatory bowel disease (IBD) characterized by immune system dysfunction and pathological overactivation of mucosal immune responses, leading to persistent inflammation and subsequent colonic mucosal injury (Raine et al., 2022)

The extent to which ascorbate or DHA are degraded by similar intracellular pathways is unknown

The stained coverslips were mounted on glass slides using one drop of aqueous mounting medium (PermaFluor # TA-030, Fisher Scientific, CA)

Thanks to Ariana for this post and all the commenters

The standard laboratory dsRNA synthesis process is expensive and yields a minimal quantity of dsRNA, making it unsuitable for extensive production demands [23]