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Currently, elevated blood concentrations of PAs (primarily spermine and/or spermidine) have been observed in cases across various subtypes of schizophrenia (8688)

This versatility, combined with its well-documented safety profile in pre-clinical models and its stable behaviour in laboratory settings, has made it one of the most widely sourced research peptides globally

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2-OHE1 and 2-OHE2 have lower estrogenic activity than E1 and E2 and have been shown to have inhibitory effects on cell growth and proliferation 36