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In addition, the other antioxidants, such as glutathione reduced ethyl ester (GSH-MEE), and -tocopherol, also suppressed the ROS formation in the starved worms subjected to gst-4 RNAi (Figs S5 and S6)
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Epigenetic mechanisms are the software that directs this process
The different hGSTP1-1 mutants show slightly altered regioselectivities in the formation of the individual GSH conjugates of clozapine which suggests that the binding orientation of the reactive nitrenium ion of clozapine is affected by the mutations [34]
This can lead to irregular heartbeat, heart attacks, and stroke
