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Although the amount of cyanide in cyanocobalamin is small, individuals with compromised detoxification pathways may benefit more from Methylcobalamin

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17 Sublingual B12 bypasses intestinal absorption issues, which makes it a more accessible treatment option for vitamin B12 deficiency

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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment