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doi: 10.1126/science.1080585 49 MuR
The transcriptional regulation of DNL is mainly orchestrated by two key transcription factors: sterol regulatory element-binding protein 1c (SREBP1c) and carbohydrate regulatory element-binding protein (ChREBP) (Sanders and Griffin, 2016)

This leads to an increase in the levels of synaptic membrane within the brain

By unraveling the mechanisms of circadian aging , we aim to illuminate novel chrono-geroprotective strategies to enhance resilience and improve quality of life across the lifespan

Tuomilehto, J
