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Cheney wants to help his patients

The most serious potential side effect of rituximab is progressive multifocal leukoencephalopathy (PML), an infection of the brain, which can manifest in a number of ways including trouble with gait, speech and memory

Elderly people due to impaired intestinal absorption and children, premenopausal women, and pregnant women whose diets are low in animal foods are all at increased risk

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Similarly, mice that lack ABHD5 in BAT have normal cold-induced thermogenesis and are not cold-sensitive, but deletion of ABHD5 in both WAT and BAT imparts cold sensitivity in the fasted state (103)