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doi: 10.1016/j.freeradbiomed.2005.04.020 189 SteinsvikEKHauskenTFlugeMellaOGiljaOH

A deficiency can develop gradually and often shows up as persistent tiredness, poor concentration, low mood, or even numbness and tingling in the hands and feet

Changing the liquid volume changes concentration, which changes the draw volume for the same target amount

PMID: 21 MalavasiFDeaglioSFunaroAFerreroEHorensteinALOrtolanEet al

People with mild B12 deficiencies experience changes in B12 effectiveness yet severe deficiencies need extended treatment time or stronger doses to produce noticeable results
