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Notably, researchers observed that the rise in p21 levels, a marker of senescence, was independent of p53, indicating that, unlike many previous drugs, AKI603-induced senescence may operate independently of p53 activity [79]

M-C Li reports grants or contracts from the National Science and Technology Council, Taiwan (NSTC 112-2410-H-003-031)

Follow-up assessments occurred on day 7 (through personal visit or phone) and day 14 (via direct interview) to evaluate medication compliance, confirmed by pill counts or blister pack checks

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doi: 10.3390/nu16162709 [DOI] [PMC free article] [PubMed] [Google Scholar] [510].Howatson G, McHugh MP, Hill J, et al