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Clinical data suggests that high-absorption glutathione directly supports the optimal function of natural killer cells and lymphocytes

To critically appraise mechanisms and levels of evidence ( in vitro, in vivo , clinical) for vitamin E and C, glutathione and its precursors, polyphenols (quercetin, resveratrol, curcumin), Crocus sativus carotenoids (crocin/safranal), and indirect modulators (e.g., omega-3, folinic acid), emphasizing study quality, translational relevance, and limitations

Furthermore, the initiation of this cascade is not instantaneousspanning from mitochondrial damage and the release of damage-associated molecular patterns (DAMPs) to immune cell metabolic reprogramming and the subsequent production of inflammatory mediators

Only the top-scoring pose per ligand was retained

YangLChenLLiDXuHChenJMinXet alEffect of GLP-1/GLP-1R on the polarization of macrophages in the occurrence and development of atherosclerosis