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7 Evidence for this hypothesis comes from studies demonstrating a variety of findings in patients with bipolar disorder including (1) abnormalities in several neurochemical markers of cerebral energy metabolism on both proton ( 1 H) and phosphorus ( 31 P) magnetic resonance spectroscopy (MRS) 8

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Significant differences between the groups were not found for all of the tested biomarkers

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Ponnatapura Janardhana

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Medini et al., 2008

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