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While there is debate about whether a human correlate to B1 cells exists, our group recently described a CD27 + IgM + CD24 hi MZ-like B cell population in the peripheral circulation of humans that produces IgM OSE and correlates with atheroprotection 132

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Some peptides, including insulin and GLP-1 medications, are FDA-approved drugs that have cleared clinical trials and are manufactured under current Good Manufacturing Practice (cGMP) standards

A protective function of IL-22BP in ischemia reperfusion and acetaminophen-induced liver injury

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