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doi:10.1111/add.12460
J.RivaA.RyanJ
It has no approval from regulatory agencies such as the FDA for human use and remains in the preclinical research phase
The group also discovered that stopping the GCPII from being active by using a drug called 2-PMPA to treat human ovarian tumors implanted in ovaries of mice, reduced tumor weights and glutamate concentrations
In atherosclerosis, VDAC1 oligomerization on the mitochondrial outer membrane permeabilizes mitochondria, facilitating ROS leakage and cytochrome c-mediated endothelial apoptosis
