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Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD)

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RNF217 was identified as a novel E3 ubiquitin ligase and was shown to play a role in mediating the degradation of FPN [30]

Caffeine is 95% metabolized by the hepatic cytochrome CYP1A2, which, additionally, is characterized by polymorphisms that affect the clearance rate of other compounds metabolized with this enzyme

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