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Description
The reasons for these failures often include short in vivo half-life, chemical instability, limited cellular uptake, poor bioavailability, lack of targeted delivery to specific tissues or (sub)cellular compartments, a narrow therapeutic index, and toxicity

People have used these leaves for centuries to sweeten teas and medicines
Theratechnologies press release (2025) 8

This medicine data has been created by - References April Hazard Vallerand, Cynthia A
95%CI: 1.0924.24) compared with the least amount of intake (Figure 5)
