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Researchers should understand that "regenerative" is a research-community grouping term, not a receptor classification

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While the causal relationship between free radicals and aging, as it was originally described, has been contradicted by more recent animal studies 2,3 , the complex association between mitochondria and aging has been consolidated and further explored 4

The metabolic kynurenic pathways is likely also implicated in ME/CFS, owing to common mutations in IDO2 (76) such as R248W and Y359STOP (77)