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431 The clinical application of copper chelation in cancer treatment is limited by poor tumor-targeting capabilities, leading to associated toxicity or ineffectiveness

[PubMed] [Google Scholar] 63.Perier C., Bov J., Wu D.-C., Dehay B., Choi D.-K., Jackson-Lewis V., Rathke-Hartlieb S., Bouillet P., Strasser A., Schulz J.B., Przedborski S., Vila M

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If ACE2 is bound to the S protein, the cellular concentration of Ang II will increase, leading to an increased presence of superoxide species and subsequent cell damage, inevitably creating a cycle of oxidative stress, and ultimately, increasing the risk of severe illness from COVID-19