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This silencing state can be reversibly lifted by the corresponding CRISPRon system, enabling dynamic regulation of gene expression [306]
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A form of the vitamin (4'-phosphopantetheine) is also required for the activity of acyl carrier protein, which is needed for the synthesis of fatty acids (28), including phospholipids and sphingolipids

doi: 10.3390/nu9050521 [DOI] [PMC free article] [PubMed] [Google Scholar] 181
