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In the SURMOUNT-1 phase-3 trial, tirzepatide produced dose-dependent weight loss reaching about ~21% of total body weight at the 15 mg dose, substantially more than placebo, with gastrointestinal symptoms the most common adverse events [6] [7]

doi: 10.1002/path.5351 93 GuS.XuM.ChenL.ShiX.LuoS.-Z

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