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However, the therapeutic promise of DFO is constrained by a critically narrow window of efficacy and challenges such as poor BBB penetration and potential systemic toxicity

Escudier S, Engel E, Pierce S, Keating M, Andreeff M

Glutathione peroxidase is a key enzyme involved in protecting cells from oxidative damage by catalysing the reduction of hydrogen peroxide and lipid peroxides

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In whole-cell voltage clamp experiments, excitatory postsynaptic currents (EPSCs) were measured at the membrane potential of 70 mV for 3 min
