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Mechanism: BPC-157 modulates the inflammatory response, helping to decrease swelling and pain

Rationale for Combination with Mesotherapy Given that mesotherapy addresses dermal matrix strength, antioxidant support and long-term pigment stabilisation, while picosecond lasers provide active pigment disruption, combining the two can yield synergistic benefits: Laser clears pigment and stimulates regeneration

486(7402):207214 Wang HM et al (2019) Inhibition of LPS-induced oxidative damages and potential anti-inflammatory effects of phyllanthus emblica extract via down-regulating NF-B, COX-2, and iNOS in RAW 264.7 cells

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If the powder does not fully dissolve in the first two to three minutes of swirling, stop and let the vial rest for one to two minutes, then swirl again