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Some authors recommend anatomopathological examination for diagnostic confirmation, although others sustain that the diagnosis is only clinical and follow-up is necessary to investigate changes in size, shape, and color of the lesion

[DOI] [PubMed] [Google Scholar] 92.Kido Y, Tamai I, Ohnari A, Sai Y, Kagami T, Nezu J, et al

Moreover, ALC and NAC mitigate Nf-kB overactivated signal, attenuating NLRP3 inflammasome pathway (IL1 and IL18) and decreasing serum TNF-alpha, IL-1, IL-6 levels, and PCR [161, 202, 217], thereby their immunomodulatory activities [161, 227, 228], and protecting against cytokine storms [82, 135, 218]

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2014;6:223ra23