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The mechanism of hepatotoxicity is unknown, but has been speculated to be caused by cellular depletion of adenosine triphosphate resulting in hepatocellular necrosis, or production of reactive oxygen species causing oxidative injury
Similarly, a number of early-onset familial AD mutations display a more aggressive disease course and a greater propensity for A to form soluble oligomeric A aggregates (Ferreira and Klein, 2011
Ferroptotic therapy in cancer: benefits, side effects, and risks

Arendt J, Skene DJ
10:403416 Li J, Goh EL, He J, Li Y, Fan Z, Yu Z, Yuan P, Liu DX (2023) Emerging intrinsic therapeutic targets for metastatic breast cancer
