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10.1007/s12311-008-0084-2 97 MarmolinoD.MantoM.AcquavivaF.VergaraP.RavellaA.MonticelliA.et al (2010)

Elevated ROS levels are associated with enhanced lipid metabolism, high lipid peroxidation, modification of cellular oxidation states, DNA breakage, changes in gene expression, or even cell death (17, 2729)

269 the expressed cDNAs of two heme dioxygenase-P450 fusion proteins converted LA to the 10( S )-HpODE

This leads to the activation of protein kinase C, which in turn regulates melanogenesis through the phosphorylation of tyrosinase (197, 198)

Spiegel, C
