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Cancer cell and T cell use of glutamine to meet energy needs is well established (reviewed in [104,105,106]), but few published studies have explored the relative use of this pathway or the balance between glucose use and glutamine use in normal B cells

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It has been noted that the upper safe limit for Se intake is around 400 g/day for adults, and exceeding this level, particularly in the long term, can lead to toxicity

The first inhibitor described for FSP1 is iFSP1, which has been shown to target the CoQ 10 binding pocket of the protein [51,101,102] (Fig