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Description
Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v

Multiple independent research groups have identified interactions between this peptide and the nitric oxide pathway, which plays a central role in vascular biology, inflammation signalling, and cellular communication

Intratumoral injection has the limitation of accessible tumors and is practically difficult in deep-seated or metastatic cases

The neurological complications progress gradually and are variable

It performs best as an adjunct, not a replacement
