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L-ascorbic acid is a co-factor for hydroxylases and monooxygenase enzymes involved in the synthesis of collagen, carnitine and neurotransmitters [21]

When combined with low-dose melatonin, bright light therapy can advance melatonin onset by nearly two hours

The Cochrane Database of Systematic Reviews , 2017 (3), CD009374

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Briefly, a line (40 pixel width) was drawn along the germline axis