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The first clinical studies mainly focus on ghrelin and ghrelin ligands as growth hormone (GH) secretagogues, thus solely measuring GH response and failing to measure serum ghrelin [249,250]
ARNTL is overexpressed in db/db mice, while the knockdown of ARNTL reduces oxidative stress in plasma and improves the classical morphological changes associated with renal ferroptosis [81]
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[DOI] [PubMed] [Google Scholar] 246
10.1371/journal.pone.0107659 PLoS One 73 DoseA.LiokatisS.TheilletF.-X.SelenkoP.SchwarzerD
