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We next examined the time course of transcription factor Nrf2 activation as Nrf2 translocated from the cytoplasm to the nucleus following combination treatment (Fig

Nevertheless, several cellular studies have suggested the protective roles of chemical anti-oxidants, such as GSH, as well as drug metabolizing enzymes, such as NQO1 and UDP-glucuronosyltransferases (UGTs), against AQ-induced cytotoxicity (Tafazoli and OBrien, 2009
Smotrys JE, Linder ME: Palmitoylation of intracellular signaling proteins: regulation and function

Rapamycin, a classic mTOR inhibitor, forms a complex with the intracellular FK506-binding protein 12 (FKBP12)

Maniyamgama et al
