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doi: 10.1016/S0741-5214(95)70188-5
And as you age, you get more autoimmunity, more cancers, et cetera, et cetera, because the immune system is not as robust

These are important context points that any clinically responsible provider will explain before therapy

Even short periods outdoors in UV-rays can lead to inflammation within the skin, which shows up as flushing or longer-lasting redness
Include leptin-deficient cohorts if mechanistic generalizability is a goal
