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Dihexa mechanism of action suggests potential for enhancing the mind-muscle connection

This, in turn, boosts metabolic rate and activates a gene known as sirtuin-1 (SIRT1), also referred to as the "longevity gene." SIRT1 is involved in reducing the risk of various conditions such as diabetes, obesity, metabolic syndrome, atherosclerosis, cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.

doi: 10.1016/s0167-4889(00)00077-x

Excessive release of zonulin results in weakening of TJ and consequent passage of antigens into the vicinity of immune cells and into the circulatory system

Treatment should start with stretching of the plantar fascia, ice massage, and nonsteroidal anti-inflammatory drugs