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In the nervous system, the IL-6/JAK/STAT pathway triggers hepcidin expression, as demonstrated in astrocytes after hemoglobin treatment and in neurons via microglial IL-6 release (Qian et al., 2014
The human clinical trial data is thinner
Musculoskeletal tissue models: Investigation of structural signaling pathways
2011;7 doi: 10.1371/journal.pgen.1001342
Biochem Biophys Res Commun (2017) 491(2):41622
