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Specifically, lactate levels have been reported to increase from 5.5 2.4 mM in grade II to 7.7 2.9 mM in grade III breast cancer, from 0.65 0.12 mM in low-grade to 1.5 0.35 mM in high-grade prostate cancer, and from 12.8 5.98 mol/g in T1 tumors to 20.54 11.60 mol/g in T4 in HNSCC

Psychiatry Res 2019;272:36-41

In MPTP mice, neurodegeneration was shown to correlate with NADPH oxidase upregulation (242)

(2024) 10:e29681

The MHRA has enforcement powers over medicines without market authorisation, and not, as we originally said, over only substances officially classified as licensed.