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The pKa is the negative logarithm of the acid dissociation constant \(K_a\)

Clin Sci (Lond) 106(3):261268

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Effect of high-glucose levels on protein oxidation in cultured lens cells, and in crystalline and albumin solution and its inhibition by vitamin B6 and N-acetylcysteine: its possible relevance to cataract formation in diabetes

Urine pH had to be 7 before starting the infusion and maintained at this level until leucovorin rescue was completed
