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Furthermore, in diabetic mice, Piezo1 overactivation was associated with excessive mitochondrial fission and reduced fusion, causing disrupted mitochondrial dynamics, impaired cardiac function and increased fibrosis [70]

A search of the PubMed public database, based on the adopted criteria, identified nine preclinical studies that validated the significance of DNA methylation as a THCA-specific biomarker, primarily in tissue and plasma samples (Table 1)

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Glp-1 receptor agonists and kidney protection

240,241 However, the use of these polymeric systems may have disadvantages that could compromise the therapeutic outcomes of peptide and protein-based drugs