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Acknowledgments NA gratefully acknowledges the partial financial supports received from FCT (Government of Portugal) through contract (SFRH/BPD/84671/2012), the Aveiro University Research Institute/CESAM (UID/AMB/50017/2013), COMPETE through Project n. FCOMP-01-0124-FEDER-02800 (FCT PTDC/AGR-PRO/4091/2012), and to FCT/MEC through national funds, and the co-funding by the FEDER, within the PT2020 Partnership Agreement and Compete 2020

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Pannala VR, Dash RK (2015) Mechanistic characterization of the thioredoxin system in the removal of hydrogen peroxide

Topical niacinamide can be effective in improving skin texture, evening out skin tone, and improving appearance of aged and photodamaged skin
They function to shuttle protons from the mitochondrial intermembrane space into the matrix along the concentration gradient, resulting in dissipation of the mitochondrial proton gradient
