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[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Singvijarn P., Manuyakorn W., Mahasirimongkol S., Wattanapokayakit S., Inunchot W., Wichukchinda N., et al

2013;3:e002373

4):S3S8

To obtain the collection of mutant plants, the seeds of thale cress Columbia (Col-0) wild-type ecotype were mutagenized with ethyl methanesulfonate ( vtc1-1 , formerly known as soz1 ) ( vtc1-1 is conferred by a semi-dominant monogenic mutation in the VTC1 gene, which maps to chromosome 2 of thale cress ( 14 C]glucose labeling assays using detached leaves with petioles of five-week-old plants, the AsA deficiency in these mutant plants is due to a biosynthetic defect ( VTC1 gene encodes the enzyme GDP-D-mannose pyrophosphorylase (GMP enzyme) ( CYT1, At2g39770 ) contains six exons and is located on chromosome 2 ( The GMP enzyme catalyzes a reversible conversion of D-mannose 1-phosphate plus GTP into GDP-D-mannose plus pyrophosphate (Wheeler et al., 1998

Evidence of -Cell dedifferentiation in human type 2 diabetes