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This stark contrast depends on the tumors metabolic demands and immune microenvironment, indicating that SQORs role is highly context-dependent

Is coenzyme Q a key factor in aging

Reporting helps build the evidence base around the real-world safety of such compounds and supports MHRA regulatory activity

Furthermore, in the course of the present invention it turned out that, if the biological sample comprises protein (typical biological samples such as cell samples or biopsy samples do, of course), it is beneficial to remove the protein from species to be measured by MS for increased accuracy and sample stability as well as reduced loss of (typically very expensive) heavy isotopologue of maleimide in the labelling reaction (which would be partially quenched by sulfhydryl groups present in protein)