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In renal proximal tubule cells, D1 signaling is linked to the inhibition of sodium transporters, Na + K + ATPase and Na + /H + exchangers (Aperia, 2000), and abnormalities in D1-like receptors contribute to increased blood pressure and hypertension, as discussed in the following text
doi: 10.1210/endrev/bnad025 69
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Hiroshi Fujii, Tohoku University, Japan Updates Copyright 2022 Maslinska, Dmowska-Chalaba and Jakubaszek
