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Redox homeostasis in the disc also plays a crucial role in the ECM anabolism and catabolism balance, and oxidative stress has been found to promote ECM degradation by interacting with various important signaling pathways in NP cells, including NF-B signaling, p38/MAPK signaling, and the Nrf2/ARE signaling pathway 17,40,41

"Clearly, I've been ripped off," she told AFP

Kaur I, Behl T, Aleya L, Rahman MH, Kumar A, Arora S, Akter R (2021) Role of metallic pollutants in neurodegeneration: effects of aluminum, lead, mercury, and arsenic in mediating brain impairment events and autism spectrum disorder

This content reflects data available as of March 2026.
