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Xc- inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism

doi: 10.2174/2405461505999200917122147 108

Integrate advanced structural tools, containing high-field NMR, cryo-EM, and AI-driven molecular dynamics, to elucidate tertiary structures and folding dynamics

The structure of GSH is unique in that the peptide bond linking glutamate and cysteine of GSH is through the -carboxyl group of glutamate rather than the conventional -carboxyl group
