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This creates a cycle where DNA damage builds up, leading to more PARP activation, which uses up even more NAD+
doi: 10.1007/s11481-013-9493-1
10.1046/j.1365-4362.2003.01908.x Nigeria
doi: 10.1016/j.ebiom.2022.104055
You rotate through these zones rather than using one spot
