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Glutathione biosynthesis occurs in two sequential, ATP-dependent enzymatic steps that take place in the cytosol: Step 1: The enzyme glutamate-cysteine ligase (GCL) combines glutamate and cysteine to form gamma-glutamylcysteine
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Development of romiplostim for the treatment of patients with chronic immune thrombocytopenia: from bench to bedside

Understanding why this occursfrom metabolic adjustment and nutrient demands to injection site reactionshelps distinguish expected responses from complications requiring medical attention

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