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Chronicles of a reductase: Biochemistry, genetics and physio-pathological role of GSNOR

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The normal histological features across all examined organs suggest that GO@GSH-FA does not induce cytotoxicity and is well-tolerated in the treated mice

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Yang and co-workers reported a nanomedicine composed of dendritic mesoporous silica nanoparticles (DMSNs), Fe 3 O 4 , Mn, and glutaminase inhibitor Telaglenastat (CB-839) (termed DFMC) for restored oxaliplatin chemosensitivity on the basis of the GSH-responsive and -exhausting effect (Figure 4C) (Figure 4D)