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P., Segal A
Also, obesity disrupts the hypothalamic-pituitary-gonadal axis, causing hypogonadism and testosterone deficiency, while adipose-mediated aromatization of testosterone to estrogen exacerbates hormonal dysregulation

Research on animals suggests that Lrrk2 p.G2019S mice had more severe colitis than controls, which results in decreased motor function and death of dopaminergic neurons (97)

In a gastric adenocarcinoma cell model of H
7 Lyme arthritis is characterized by severe joint pain and swelling in the knee and other large joints
