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Key Benefits Brightening Effect : Glutathione reduces pigmentation and promotes a more even skin tone

While certain senolytic compounds have shown specificity for senescent cells in preclinical models, achieving this selectivity in humans remains a significant hurdle.120 For example, some senescence-associated proteins (eg, BCL-2, p53, SASP factors) are also expressed in normal, proliferating cells, leading to potential off-target effects.31 Therefore, optimizing senolytic agents to minimize side effects while maintaining efficacy is crucial

Gerace, E

Shih AY, Damm-Ganamet KL, Mirzadegan T

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