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Plant Physiol 168:16031615 Zhao FJ, Hawkesford MJ, McGrath SP (1999) Sulphur assimilation and effects on yield and quality of wheat

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The antisense strand (guide strand) then binds to the mRNA target sequences, leading to one of two outcomes: either cleavage facilitated by the action of argonaute protein transcription [21, 38] or regulation of the target sequences by recruiting accessory factors through participation in the synthesis of Piwi-interacting RNAs (piRNAs)