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10.1016/j.cjca.2012.03.013 17 ButkowskiE

Human clinical trials have not been completed, meaning efficacy and safety in people is not established through rigorous research

Cells were treated for 24 h with 0.1600 M NNMT inhibitors in cell culture media

UK patients should consult their GP and report any suspected adverse effects to the MHRA via the Yellow Card Scheme

25 Structuralactivity relationship (SAR) studies on 1-MQ showed that small substituents like methyl or amino groups on 1-MQ were tolerated, while bulky groups on 1-MQ lost binding affinity due to steric effects
