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10.1016/j.cjca.2012.03.013 17 ButkowskiE

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Human clinical trials have not been completed, meaning efficacy and safety in people is not established through rigorous research

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Cells were treated for 24 h with 0.1600 M NNMT inhibitors in cell culture media

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UK patients should consult their GP and report any suspected adverse effects to the MHRA via the Yellow Card Scheme

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25 Structuralactivity relationship (SAR) studies on 1-MQ showed that small substituents like methyl or amino groups on 1-MQ were tolerated, while bulky groups on 1-MQ lost binding affinity due to steric effects

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