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For example, normalization of ALT and AST levels can alleviate symptoms of liver dysfunction such as fatigue, abdominal discomfort, and jaundice, thereby improving patients quality of life and daily activity ability

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In HFD-induced obese insulin-resistant rats subjected to cardiac ischemiareperfusion injury, dapagliflozin, an SGLT2 inhibitor, exhibited superior cardioprotective efficacy compared with vildagliptin, a DPP-4 inhibitor, as evidenced by suppression of mitochondrial Drp1 expression, reduced infarct size, and improved left ventricular function [199]

Food Bioscience, 46 , Article 101592

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