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Moreover, while the iron is a substrate of ferrochelatase (FECH), the defective enzyme in the EPP, it is the limiting substrate in XLP caused by a gain of function of ALAS2

A., Ryan, B

Chen Y, Chai Y, Yin B, Zhang X, Han X, Cai L, Yin N, Li F

10.1126/scitranslmed.adg8357

Long-term GH elevation also carries theoretical cancer concerns, as GH and IGF-1 can promote cell growth
